Compile Data Set for Download or QSAR
Found 301 of ic50 data for polymerid = 2762
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444320(US10660898, Example 70)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444306(US10660898, Example 25)copy SMILEScopy InChI
Affinity DataIC50: 0.251nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444315(US10660898, Example 53)copy SMILEScopy InChI
Affinity DataIC50: 0.501nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444311(US10660898, Example 39)copy SMILEScopy InChI
Affinity DataIC50: 0.631nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50579668(CHEMBL5091438)copy SMILES
Affinity DataIC50: 0.794nMAssay Description:Inhibition of PIK3C2B (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZVJPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM489258(2-[(1S)-1-Cyclopropylethyl]-6-(4-methyl-2-{[6-(3-o...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PIK3C2B (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZVJPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444319(US10660898, Example 63)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444301(US10660898, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444314(US10660898, Example 50)copy SMILEScopy InChI
Affinity DataIC50: 1.26nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444297(US10660898, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444321(US10660898, Example 72)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444312(US10660898, Example 41)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444298(US10660898, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444316(US10660898, Example 54)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444302(US10660898, Example 17)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444300(US10660898, Example 14)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50512861(CHEMBL4558527)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PIK3C2B (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZVJPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444313(US10660898, Example 43)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50059637(GSK-2636771 | GSK2636771 | US10660898, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444304(US10660898, Example 20)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444318(US10660898, Example 59)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444317(US10660898, Example 58)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444299(US10660898, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444303(US10660898, Example 18)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28053F2PubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928M7PubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444308(US10660898, Example 32)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444305(US10660898, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3K-C2betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46S8HPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444322(US10660898, Example 73)copy SMILEScopy InChI
Affinity DataIC50: 25.1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MWRPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50197065(CHEMBL3913354)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of PI3KC2beta (unknown origin) expressed in HEK293 cells using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1TPXPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50394846(CHEMBL2165017 | US8772480, 35)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of PIK3C2betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50274638(CHEMBL4126156 | US10858355, Example 4)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BFZPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50042923(CHEMBL3354566)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MWRPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant PI3KC2beta using substrate PI incubated for 1 hr by Adapta kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1TPXPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444309(US10660898, Example 35)copy SMILEScopy InChI
Affinity DataIC50: 63.1nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM81368(PIK90)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MWRPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM81368(PIK90)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of PI3KC2beta (unknown origin) expressed in HEK293 cells using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1TPXPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348119(US9790228, Compound 38)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348131(US9790228, Compound 197 | US9790228, Compound 50)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM444310(US10660898, Example 38)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8GTTUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348255(US9790228, Compound 174)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM50323731(CHEMBL1213117 | N-(6-(4-amino-1-((2-(4-methylpiper...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348245(US9790228, Compound 164)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM25036(CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X928M7PubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348244(US9790228, Compound 163)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1HXZPubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348220(US9790228, Compound 139)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
GLAXOSMITHKLINE LLC

US Patent
LigandPNGBDBM348211(US9790228, Compound 130)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112FVUS Patent
Displayed 1 to 50 (of 301 total ) | Next | Last >>
Jump to: